TPH2, tryptophan hydroxylase 2, 121278

N. diseases: 137; N. variants: 37
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C4017088
Disease: UNIPOLAR DEPRESSION, SUSCEPTIBILITY TO
UNIPOLAR DEPRESSION, SUSCEPTIBILITY TO 		phenotype Finding 1 1 0.100 None 0 1
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		disease Mental Disorders Mental or Behavioral Dysfunction 641 225 0.800 None 0.800 32 5 2004 2019
CUI: C0040188
Disease: Tic disorder
Tic disorder 		disease Nervous System Diseases; Mental Disorders Mental or Behavioral Dysfunction 33 4 0.010 None 1.000 1 2 2013 2013
CUI: C0438696
Disease: Suicidal
Suicidal 		disease Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 93 29 0.060 None 1.000 6 2005 2015
CUI: C0038644
Disease: Sudden infant death syndrome
Sudden infant death syndrome 		disease Pathological Conditions, Signs and Symptoms Disease or Syndrome 140 68 0.020 None 1.000 2 2008 2016
CUI: C0038586
Disease: Substance Use Disorders
Substance Use Disorders 		group Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 218 16 0.320 None 0.500 2 1 2010 2015
CUI: C0038443
Disease: Stress, Psychological
Stress, Psychological 		disease Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 199 24 0.010 None 1.000 1 2016 2016
CUI: C0038441
Disease: Stress Disorders, Traumatic
Stress Disorders, Traumatic 		group Mental Disorders Mental or Behavioral Dysfunction 20 0.010 None 1.000 1 2013 2013
CUI: C0588008
Disease: Severe depression
Severe depression 		disease Mental Disorders Mental or Behavioral Dysfunction 46 2 0.010 None 1.000 1 1 2019 2019
CUI: C1445957
Disease: Serum total cholesterol measurement
Serum total cholesterol measurement 		phenotype Laboratory Procedure 486 1243 0.100 None 1.000 1 1 2012 2012
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		disease Pathological Conditions, Signs and Symptoms Acquired Abnormality 249 21 0.010 None 1.000 1 2019 2019
CUI: C0085271
Disease: Self-Injurious Behavior
Self-Injurious Behavior 		phenotype Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 91 9 0.010 None 1.000 1 2010 2010
CUI: C0232600
Disease: Self-induced vomiting
Self-induced vomiting 		disease Pathological Conditions, Signs and Symptoms Mental or Behavioral Dysfunction 4 1 0.020 None 1.000 2 1 2011 2013
CUI: C0085159
Disease: Seasonal Affective Disorder
Seasonal Affective Disorder 		disease Mental Disorders Mental or Behavioral Dysfunction 57 17 0.020 None 1.000 2 2013 2015
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		disease Mental Disorders Mental or Behavioral Dysfunction 2872 2897 0.400 None 0.500 12 4 2005 2018
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		disease Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases Disease or Syndrome 2723 2387 0.010 None 1.000 1 2012 2012
CUI: C2169806
Disease: recurrent muscle twitches (symptom)
recurrent muscle twitches (symptom) 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases Sign or Symptom 26 7 0.010 None 1.000 1 2 2013 2013
CUI: C0033975
Disease: Psychotic Disorders
Psychotic Disorders 		group Mental Disorders Mental or Behavioral Dysfunction 560 179 0.320 None 1.000 3 2 2006 2014
CUI: C1571984
Disease: Psychosis, Involutional
Psychosis, Involutional 		disease Mental Disorders Mental or Behavioral Dysfunction 25 0.300 None 0
CUI: C0815107
Disease: psychological distress
psychological distress 		disease Mental or Behavioral Dysfunction 87 10 0.010 None < 0.001 1 2014 2014
CUI: C0233401
Disease: Psychiatric symptom
Psychiatric symptom 		phenotype Sign or Symptom 95 12 0.010 None 1.000 1 2011 2011
CUI: C4331029
Disease: Primary Pigmented Nodular Adrenal Dysplasia
Primary Pigmented Nodular Adrenal Dysplasia 		disease Congenital Abnormality 31 1 0.010 None 1.000 1 2016 2016
CUI: C0033139
Disease: Primary Insomnia
Primary Insomnia 		disease Nervous System Diseases; Mental Disorders Disease or Syndrome 7 2 0.010 None 1.000 1 1 2018 2018
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder 		disease Mental Disorders Mental or Behavioral Dysfunction 418 117 0.040 None 1.000 4 2 2012 2019
CUI: C0031572
Disease: Phobia, Social
Phobia, Social 		disease Mental Disorders Mental or Behavioral Dysfunction 33 8 0.010 None 1.000 1 2016 2016